‘Good Sam’ reunites Sophia Bush, Hilarie Burton & Bethany Joy Lenz (PHOTOS)

Brooke, Haley and Peyton share the small screen once again! Sophia Bushs Good Sam welcomed A hill of trees‘s Bethany Joy Lenz and Hilarie Burton guest-star on the March 23 episode, and it’s up to the titular doctor to save one of them.

In Keep Talking, Lenz plays Amy Taylor, who is hospitalized with signs of premature heart disease. Burton’s Gretchen is her sister who accompanies her. While treating her, Bush’s Dr. Sam Griffith has a deeper secret. Check out the photos below to see how Sam, Dr. Rob “Griff” Griffith (Jason Isaacs), Dr. Lex Trulie (Skye P. Marshall) and Dr. Caleb Tucker (Michael Stahl-David) treating Amy. Also, it looks like Gretchen has her own thoughts about her sister’s treatment and conflicts between the siblings could arise.

Elsewhere in the episode, Griff eagerly awaits the results of his MIR in hopes of getting to the root of his troubling symptoms. What does this mean for his future as a doctor?

Scroll down to take a look at Keep Talk.

Good SamWednesdays, 10/9c, CBS