How to alleviate depression in older adults

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Depression is common in older adults.

But treatment with standard drugs, so-called antidepressants, does not always work.

If depression persists after trying some of these drugs, it’s not clear what approach might be best.

Researchers studied over 600 adults ages 60 and older with intractable depression. The participants were divided into three groups.

One group added the drug aripiprazole (Abilify) to their prescribed antidepressant. The second group added an antidepressant called bupropion (Wellbutrin).

The third group stopped taking their prescribed antidepressant and switched to bupropion.

After 10 weeks, the group that added aripiprazole showed the most improvement. They experienced a significant increase in well-being compared to the group that switched to bupropion.

The groups that took one of the additional drugs had fewer symptoms of depression than the group that switched to bupropion.

Symptoms improved in 29% of patients adding aripiprazole and 28% of patients adding bupropion. But only 19% of those who switched to bupropion improved.

“When a patient does not respond to the first treatment they are prescribed for depression, doctors often follow a pattern of trying one treatment at a time until they get an effective drug,” says lead researcher Dr. Eric J. Lenze of Washington University St. Louis.

“It would be beneficial to have an evidence-based strategy that we can rely on to get patients better as quickly as possible.”

If you are interested in stroke, please read the relevant studies A diet high in flavonoids could help reduce the risk of strokeAnd A MIND diet could slow cognitive decline after a stroke.

For more information on depression, see recent studies on one of the major causes of depression in older people. The results show that new drugs could fight depression in just two hours.


Laura Coffey

Laura Coffey is a Worldtimetodays U.S. News Reporter based in Canada. His focus is on U.S. politics and the environment. He has covered climate change extensively, as well as healthcare and crime. Laura Coffey joined Worldtimetodays in 2023 from the Daily Express and previously worked for Chemist and Druggist and the Jewish Chronicle. He is a graduate of Cambridge University. Languages: English. You can get in touch with me by emailing: LauraCoffey@worldtimetodays.com.

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