Researchers find a drug that extends lifespan
Scientists from the University of Auckland have conducted an intriguing study of the effects of alpelisib, a drug typically used to treat cancer.
The aim of their research was to investigate whether this drug can also influence the aging process.
The Experiment: Alpelisib and Aging
In the experiment, a group of healthy mice received a normal diet, while another group received the same diet with alpelisib.
Drug treatment began when the mice were middle-aged (about a year old) and lasted for a longer period of time.
The scientists found that mice given the diet supplemented with alpelisib lived about 10% longer, about three years on average.
The drug-treated mice also showed improved health indicators as they aged, such as improved coordination and strength.
Attention: Possible disadvantages and side effects
Despite the exciting results, the researchers advise caution when considering the potential use of the drug in humans.
Although the treated mice lived longer, they showed some negative traits of aging, including reduced bone mass. In addition, alpelisib has side effects that may prove harmful if taken for a long time.
The bigger picture: alpelisib, PI 3-kinase and aging
Alpelisib’s importance goes beyond its current use in cancer treatment. It targets an enzyme called PI-3-kinase, which scientists believe has a role in both cancer and aging.
For over two decades, researchers have been developing drugs that target PI-3 kinase, with a major focus on cancer treatment.
This study suggests that these drugs could have broader uses, such as extending lifespan and treating metabolic diseases.
More research is needed to fully understand the effects of alpelisib on aging and to identify potential risks associated with its use.
Nonetheless, this study represents an important step in the timeless quest to extend human life and improve health.
More recent research on aging and longevity
The Auckland study is not alone in its pursuit. Other recent research suggests that animal protein may be more beneficial for aging muscle than plant-based protein.
Another study suggests that olive oil could contribute to longer life, while vitamin D has been linked to a lower risk of autoimmune diseases.
These results underscore the importance of long-term research into aging and disease mechanisms.
They also underscore the need to explore new treatments and therapies that could improve human health and extend lifespan.
The quest for longevity continues, and each study brings us a step closer to understanding the complex process of aging.
If you care about heart health, please read studies about it The best blood glucose levels to prevent strokes and heart attacksAnd Vitamin K can reduce your risk of heart disease by a third.
For more information on heart health, see recent studies on Why obesity increases heart damage in COVID-19and results are displayed This drug combination can halve your risk of heart attack and stroke.
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