Social isolation can be a major cause of depression in adults

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Depression is a global mental disorder that affects millions of people and significantly impacts everyone’s quality of life.

A recent study by a team of scientists from Colorado State University has shed light on the factors that contribute to depression. Social isolation was identified as the main risk factor in middle-aged and older adults.


The research team used a machine learning approach, a subset of artificial intelligence, to examine data from a large, population-representative sample of middle-aged and older adults in Europe.

The machine learning model was trained on 56 variables, including demographic factors, health status, and socioeconomic indicators, to identify patterns and associations that might predict risk of depression.


Among the many variables examined, social isolation turned out to be the main risk factor for depression in both men and women.

This finding highlights the detrimental impact of loneliness and lack of social interaction on people’s mental health, especially in old age.

It has been found that after social isolation, generally poor health and mobility difficulties are major contributors to depression.

The research team also analyzed 30 variables related to the participants’ social networks and family configurations.

These factors included frequency of contact with friends and family, number of friends, and interpersonal transactions related to physical care and financial support.

The fourth major risk factor identified in men is difficulty with important activities of daily living, such as managing finances, taking medication, and using the phone.

For women, a family burden emerged as the fourth significant risk factor, with women who strongly agreed with the statement “Family responsibilities prevent me from doing the things I want to do” being at an increased risk of depression.

However, the study found that these gender-related factors accounted for only a small portion of the differences in depression risk, suggesting that depression is influenced by a complex interplay of factors.


The results of this study underscore the importance of social support and connectedness in reducing the risk of depression, particularly in middle-aged and older adults.

The researchers, led by Stephen Aichele, believe that understanding various risk and protective factors for depression can guide interventions to more effectively prevent and treat depression.

Given the strong association between self-reported social isolation and depression, the research team suggests that healthcare providers pay particular attention to different dimensions of social and relational support when working with patients at risk of depression.

The researchers also advocate for more studies looking at the complexities of social and relational support to better understand how it relates to mental health.


This study, published in The Lancet Regional Health—Europe, is a reminder of the crucial role social connections play in our mental well-being.

As people age, these connections can become even more important, highlighting the need for initiatives that counteract social isolation and promote social engagement among middle-aged and older adults.

Ultimately, the researchers hope their findings will help improve depression prevention and intervention strategies and pave the way for better mental health outcomes for millions of people worldwide.

If you are interested in depression, please read the relevant studies Eating a vegetarian diet can increase your risk of depression. And Vitamin D could help relieve symptoms of depression.

Further information on the subject of health can be found in current studies Highly processed foods can make you feel depressed. And These antioxidants could help reduce the risk of dementia.

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